2KAV
Solution structure of the human Voltage-gated Sodium Channel, brain isoform (Nav1.2)
Summary for 2KAV
| Entry DOI | 10.2210/pdb2kav/pdb |
| Related | 1byy 1qg9 |
| NMR Information | BMRB: 16032 |
| Descriptor | Sodium channel protein type 2 subunit alpha (1 entity in total) |
| Functional Keywords | voltage-gated sodium channel, alternative splicing, disease mutation, epilepsy, glycoprotein, ion transport, ionic channel, membrane, polymorphism, sodium, sodium channel, sodium transport, transmembrane, transport, ubl conjugation, voltage-gated channel, transport protein, transport protein regulator |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Multi-pass membrane protein: Q99250 |
| Total number of polymer chains | 1 |
| Total formula weight | 14591.39 |
| Authors | Miloushev, V.Z.,Levine, J.A.,Arbing, M.A.,Hunt, J.F.,Pitt, G.S.,Palmer, A.G. (deposition date: 2008-11-15, release date: 2009-01-06, Last modification date: 2022-03-16) |
| Primary citation | Miloushev, V.Z.,Levine, J.A.,Arbing, M.A.,Hunt, J.F.,Pitt, G.S.,Palmer, A.G. Solution structure of the NaV1.2 C-terminal EF-hand domain. J.Biol.Chem., 284:6446-6454, 2009 Cited by PubMed: 19129176DOI: 10.1074/jbc.M807401200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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