2JZQ
Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures
Summary for 2JZQ
| Entry DOI | 10.2210/pdb2jzq/pdb |
| Descriptor | Insulin (1 entity in total) |
| Functional Keywords | hormone, single chain insulin, mutant, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, pharmaceutical, secreted |
| Cellular location | Secreted: P01308 |
| Total number of polymer chains | 1 |
| Total formula weight | 6382.19 |
| Authors | Hua, Q.X.,Nakarawa, S.,Jia, W.H.,Huang, K.,Philips, N.F.,Hu, S.Q.,Weiss, M.A. (deposition date: 2008-01-11, release date: 2008-02-26, Last modification date: 2021-10-20) |
| Primary citation | Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Huang, K.,Phillips, N.B.,Hu, S.Q.,Weiss, M.A. Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications. J.Biol.Chem., 283:14703-14716, 2008 Cited by PubMed: 18332129DOI: 10.1074/jbc.M800313200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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