2JZQ

Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Insulin	polymer	57	6382.2	1	UniProt (P01308) Pfam (PF00049)

Sequence modifications

A: 1 - 30 (UniProt: P01308)

PDB	External Database	Details
Asp 10	His 34	engineered mutation
Asp 28	Pro 52	engineered mutation
Pro 29	Lys 53	engineered mutation

A: 37 - 57 (UniProt: P01308)

PDB	External Database	Details
Gly 31	-	linker
Gly 32	-	linker
Gly 33	-	linker
Pro 34	-	linker
Arg 35	-	linker
Arg 36	-	linker
His 44	Thr 97	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	6382.2
All*	Total formula weight	6382.2

*Water molecules are not included.