2JIX
Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor
Summary for 2JIX
Entry DOI | 10.2210/pdb2jix/pdb |
Related | 1CN4 1EBA 1EBP 1EER 1ERN |
Descriptor | ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR (3 entities in total) |
Functional Keywords | immune system, receptor, transmembrane, receptor soluble domain, antibody, receptor-immune system complex, receptor/immune system |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 9 |
Total formula weight | 213148.86 |
Authors | Liu, Z.,Stoll, V.S.,DeVries, P.,Jakob, C.G.,Xie, N.,Simmer, R.L.,Lacy, S.E.,Egan, D.A.,Harlan, J.E.,Lesniewski, R.R.,Reilly, E.B. (deposition date: 2007-07-02, release date: 2007-07-10, Last modification date: 2020-03-18) |
Primary citation | Liu, Z.,Stoll, V.S.,Devries, P.,Jakob, C.G.,Xie, N.,Simmer, R.L.,Lacy, S.E.,Egan, D.A.,Harlan, J.E.,Lesniewski, R.R.,Reilly, E.B. A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site. Blood, 110:2408-, 2007 Cited by PubMed: 17620453DOI: 10.1182/BLOOD-2007-04-083998 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report