2JHM

Structure of globular heads of M-ficolin at neutral pH

Summary for 2JHM

• Entry DOI: 10.2210/pdb2jhm/pdb
• Related: 2JHH 2JHI 2JHK 2JHL
• Descriptor: FICOLIN-1, CALCIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: lectin, collagen, acidic ph, complement, glycoprotein, polymorphism, innate immunity, sugar-binding protein, sugar binding protein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 24714.40

Authors

Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C. (deposition date: 2007-02-22, release date: 2007-10-09, Last modification date: 2023-12-13)

• Primary citation: Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Fujita, T.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C.; Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.; J.Biol.Chem., 282:35814-, 2007; PubMed: 17897951; DOI: 10.1074/JBC.M705741200

Experimental method

X-RAY DIFFRACTION (1.52 Å)