2JHM
Structure of globular heads of M-ficolin at neutral pH
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA F1298 |
| Chain | Residue |
| F | ASP233 |
| F | ASP235 |
| F | SER237 |
| F | SER239 |
| F | HOH2106 |
| F | HOH2107 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE F1299 |
| Chain | Residue |
| F | GLU291 |
| F | HOH2014 |
| F | HOH2064 |
| F | LEU116 |
| F | ASP118 |
| F | ARG131 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA F1300 |
| Chain | Residue |
| F | PHE245 |
| F | CYS254 |
| F | HIS255 |
| F | ALA272 |
| F | HOH2147 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17148457, ECO:0000269|PubMed:17897951, ECO:0000269|PubMed:20032467, ECO:0007744|PDB:2D39, ECO:0007744|PDB:2WNP |
| Chain | Residue | Details |
| F | ASP233 | |
| F | ASP235 | |
| F | SER237 | |
| F | SER239 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17897951 |
| Chain | Residue | Details |
| F | ASP253 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Mediates specificity for sialic acids => ECO:0000305|PubMed:17897951, ECO:0000305|PubMed:20032467 |
| Chain | Residue | Details |
| F | TYR271 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Mediates specificity for sialic acids => ECO:0000305|PubMed:17897951 |
| Chain | Residue | Details |
| F | TYR283 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| F | ASN276 |
