2JAJ
DDAH1 complexed with L-257
Summary for 2JAJ
Entry DOI | 10.2210/pdb2jaj/pdb |
Related | 1H70 2JAI |
Descriptor | NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1, N~5~-{IMINO[(2-METHOXYETHYL)AMINO]METHYL}-L-ORNITHINE (3 entities in total) |
Functional Keywords | ddah, hydrolase, nitric oxide synthase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 63438.89 |
Authors | Murray-Rust, J.,O'Hara, B.P.,Rossiter, S.,Leiper, J.M.,Vallance, P.,McDonald, N.Q. (deposition date: 2006-11-29, release date: 2007-02-13, Last modification date: 2024-05-01) |
Primary citation | Leiper, J.,Nandi, M.,Torondel, B.,Murray-Rust, J.,Malaki, M.,O'Hara, B.,Rossiter, S.,Anthony, S.,Madhani, M.,Selwood, D.,Smith, C.,Wojciak-Stothard, B.,Rudiger, A.,Stidwill, R.,McDonald, N.Q.,Vallance, P. Disruption of methylarginine metabolism impairs vascular homeostasis. Nat. Med., 13:198-203, 2007 Cited by PubMed: 17273169DOI: 10.1038/nm1543 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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