2IT5
Crystal Structure of DCSIGN-CRD with man6
Summary for 2IT5
Entry DOI | 10.2210/pdb2it5/pdb |
Related | 2IT6 |
Descriptor | CD209 antigen, DCSIGN-CRD, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | c-type lectin, protein carbohydrate complex, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 16755.46 |
Authors | Weis, W.I.,Feinberg, H.,Castelli, R.,Drickamer, K.,Seeberger, P.H. (deposition date: 2006-10-19, release date: 2006-12-05, Last modification date: 2023-08-30) |
Primary citation | Feinberg, H.,Castelli, R.,Drickamer, K.,Seeberger, P.H.,Weis, W.I. Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins. J.Biol.Chem., 282:4202-4209, 2007 Cited by PubMed: 17150970DOI: 10.1074/jbc.M609689200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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