2I6A
Human Adenosine Kinase in Complex With 5'-Deoxy-5-Iodotubercidin
Summary for 2I6A
Entry DOI | 10.2210/pdb2i6a/pdb |
Related | 2I6B |
Descriptor | Adenosine kinase, 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE (3 entities in total) |
Functional Keywords | protein-ligand complex, 5'-deoxy-5-iodotubercidin, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 156525.48 |
Authors | Muchmore, S.W. (deposition date: 2006-08-28, release date: 2007-01-02, Last modification date: 2024-02-21) |
Primary citation | Muchmore, S.W.,Smith, R.A.,Stewart, A.O.,Cowart, M.D.,Gomtsyan, A.,Matulenko, M.A.,Yu, H.,Severin, J.M.,Bhagwat, S.S.,Lee, C.H.,Kowaluk, E.A.,Jarvis, M.F.,Jakob, C.L. Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes. J.Med.Chem., 49:6726-6731, 2006 Cited by PubMed: 17154503DOI: 10.1021/jm060189a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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