2I26

Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme

Summary for 2I26

• Entry DOI: 10.2210/pdb2i26/pdb
• Related: 2I24 2I25 2I27
• Descriptor: New Antigen Receptor Ancestral, Lysozyme C, SULFATE ION, ... (4 entities in total)
• Functional Keywords: immunoglobulin fold, protein-protein complex, immune system
• Biological source: Ginglymostoma cirratum (nurse shark); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 6
• Total formula weight: 83453.22

Authors

Stanfield, R.L.,Wilson, I.A. (deposition date: 2006-08-15, release date: 2007-03-06, Last modification date: 2011-07-13)

• Primary citation: Stanfield, R.L.,Dooley, H.,Verdino, P.,Flajnik, M.F.,Wilson, I.A.; Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.; J.Mol.Biol., 367:358-372, 2007; PubMed: 17258766; DOI: 10.1016/j.jmb.2006.12.045

Experimental method

X-RAY DIFFRACTION (2.5 Å)