2HL3

Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex with human EB1 C-terminal hexapeptide

Summary for 2HL3

Entry DOI	10.2210/pdb2hl3/pdb
Related	1TXQ 2COY 2HKN 2HL3 2HL5
Descriptor	Dynactin-1, Microtubule-associated protein RP/EB family member 1 (3 entities in total)
Functional Keywords	microtubule binding, dynactin, cytoskeleton associated protein, p150glued, eb1, +tip protein complex structure, eey/f-coo- sequence motif, clip-170, alpha-tubulin, structural protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm : Q14203 Cytoplasm, cytoskeleton: Q15691
Total number of polymer chains	3
Total formula weight	21564.84
Authors	Honnappa, S.,Winkler, F.K.,Steinmetz, M.O. (deposition date: 2006-07-06, release date: 2006-09-12, Last modification date: 2024-02-14)
Primary citation	Honnappa, S.,Okhrimenko, O.,Jaussi, R.,Jawhari, H.,Jelesarov, I.,Winkler, F.K.,Steinmetz, M.O. Key interaction modes of dynamic +TIP networks. Mol.Cell, 23:663-671, 2006 Cited by PubMed: 16949363 DOI: 10.1016/j.molcel.2006.07.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation