2HL3
Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex with human EB1 C-terminal hexapeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dynactin-1 | polymer | 97 | 10369.5 | 2 | UniProt (Q14203) Pfam (PF01302) In PDB | Homo sapiens (human) | 150 kDa dynein-associated polypeptide, DP-150, DAP-150, p150-glued, p135 |
| 2 | C | Microtubule-associated protein RP/EB family member 1 | polymer | 6 | 825.8 | 1 | UniProt (Q15691) In PDB | APC-binding protein EB1, End-binding protein 1, EB1 | |
| 3 | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 111 (UniProt: Q14203)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | cloning artifact |
| Ser 16 | - | cloning artifact |
| His 17 | - | cloning artifact |
| Met 49 | Ala 49 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 21564.8 | |
| All* | Total formula weight | 21564.8 |
