2GIT

Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide

Summary for 2GIT

• Entry DOI: 10.2210/pdb2git/pdb
• Related: 1DUZ 2AV1 2AV7
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Transcriptional activator TAX, ... (7 entities in total)
• Functional Keywords: htlv-1 tax peptide, haptenated peptide, lysine-4-(3-indolyl)-butyric acid, mhc class i, hla-a2, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: Q9TQH5; Secreted: P61769
• Total number of polymer chains: 6
• Total formula weight: 90529.47

Authors

Borbulevych, O.Y.,Baker, B.M. (deposition date: 2006-03-29, release date: 2006-10-03, Last modification date: 2023-08-30)

• Primary citation: Gagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Turner, R.V.,Damirjian, M.,Wojnarowicz, A.,Biddison, W.E.,Baker, B.M.; T Cell Receptor Recognition via Cooperative Conformational Plasticity.; J.Mol.Biol., 363:228-243, 2006; PubMed: 16962135; DOI: 10.1016/j.jmb.2006.08.045

Experimental method

X-RAY DIFFRACTION (1.7 Å)