2FIR
Crystal structure of DFPR-VIIa/sTF
Summary for 2FIR
Entry DOI | 10.2210/pdb2fir/pdb |
Related | 1DAN 2A2Q 2AER 2B8O |
Related PRD ID | PRD_000021 |
Descriptor | Coagulation factor VII Light chain, ZINC ION, CHLORIDE ION, ... (12 entities in total) |
Functional Keywords | factor viia, soluble tissue factor, oxyanion hole, serine protease, blood coagulation, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 69134.80 |
Authors | Bajaj, S.P.,Schmidt, A.E.,Padmanabhan, K.,Bajaj, M.S.,Prevost, D.,Schreuder, H. (deposition date: 2005-12-30, release date: 2006-07-11, Last modification date: 2020-07-29) |
Primary citation | Bajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K. High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa J.Biol.Chem., 281:24873-24888, 2006 Cited by PubMed: 16757484DOI: 10.1074/jbc.M509971200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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