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2FIR

Crystal structure of DFPR-VIIa/sTF

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
Coagulation factor VII Light chainpolymer14216359.81UniProt (P08709)
Pfam (PF00594)
Pfam (PF00008)
Pfam (PF14670)
Homo sapiens (human)
2B
(H)
Coagulation factor VII Heavy Chain (EC 3.4.21.21)polymer25428103.31UniProt (P08709)
Pfam (PF00089)
Homo sapiens (human)
3C
(T)
Tissue factorpolymer20523302.91UniProt (P13726)
Pfam (PF01108)
Pfam (PF09294)
Homo sapiens (human)TF, Coagulation factor III, Thromboplastin, CD142 antigen
4D
(L)
alpha-D-glucopyranosenon-polymer180.21Chemie (GLC)
5E
(L)
alpha-L-fucopyranosenon-polymer164.21Chemie (FUC)
6F, I, L
(L)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
7G, H, J, K, M...
(L, H)
CALCIUM IONnon-polymer40.16Chemie (CA)
8N
(H)
D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamidenon-polymer451.01BIRD (PRD_000021)
Chemie (0G7)
9P
(H)
SODIUM IONnon-polymer23.01Chemie (NA)
10Q, R
(H)
ZINC IONnon-polymer65.42Chemie (ZN)
11S, T, U
(H, T)
CHLORIDE IONnon-polymer35.53Chemie (CL)
12V, W, X
(L, H, T)
waterwater18.0626Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight67766.0
Non-Polymers*Number of molecules18
Total formula weight1368.8
All*Total formula weight69134.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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