2FCW

Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the Receptor Associated Protein (RAP).

Summary for 2FCW

Entry DOI	10.2210/pdb2fcw/pdb
Descriptor	Alpha-2-macroglobulin receptor-associated protein, Low-density lipoprotein receptor, SODIUM ION, ... (6 entities in total)
Functional Keywords	protein-protein complex, rap, ldlr, escort protein, calcium-binding, lipid transport-endocytosis-chaperone complex, lipid transport/endocytosis/chaperone
Biological source	Homo sapiens (human) More
Cellular location	Endoplasmic reticulum: P30533 Cell membrane; Single-pass type I membrane protein: P01130
Total number of polymer chains	2
Total formula weight	22363.92
Authors	Beglova, N.,Fisher, C.,Blacklow, S.C. (deposition date: 2005-12-12, release date: 2006-05-16, Last modification date: 2024-04-03)
Primary citation	Fisher, C.,Beglova, N.,Blacklow, S.C. Structure of an LDLR-RAP Complex Reveals a General Mode for Ligand Recognition by Lipoprotein Receptors Mol.Cell, 22:277-283, 2006 Cited by PubMed: 16630895 DOI: 10.1016/j.molcel.2006.02.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.26 Å)

Structure validation