Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0008201 | molecular_function | heparin binding |
| A | 0048019 | molecular_function | receptor antagonist activity |
| A | 0050750 | molecular_function | low-density lipoprotein particle receptor binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 3001 |
| Chain | Residue |
| B | PHE105 |
| B | ASP108 |
| B | ASP110 |
| B | ASP112 |
| B | ASP118 |
| B | GLU119 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 3002 |
| Chain | Residue |
| B | ASP151 |
| B | ASP157 |
| B | GLU158 |
| B | TRP144 |
| B | ASP147 |
| B | ASP149 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 5001 |
| Chain | Residue |
| A | HOH61 |
| A | HOH73 |
| A | GLU265 |
| A | GLU265 |
| A | GLU269 |
| B | HOH5023 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 5002 |
| Chain | Residue |
| B | LYS86 |
| B | GLY98 |
| B | HOH5003 |
| B | HOH5004 |
| B | HOH5012 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 5003 |
| Chain | Residue |
| A | HOH68 |
| A | HOH110 |
| A | ASP228 |
| A | SER232 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 5004 |
| Chain | Residue |
| A | HOH56 |
| A | HOH91 |
| A | HOH121 |
| A | LEU240 |
| B | HOH5014 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD A 4001 |
| Chain | Residue |
| A | HIS259 |
| B | ASP151 |
| B | GLU153 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 4002 |
| Chain | Residue |
| A | HOH145 |
| A | GLU217 |
| A | PHE218 |
| A | ARG244 |
| A | LYS248 |
| A | LYS298 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MPD B 4003 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 4004 |
| Chain | Residue |
| B | PRO129 |
| B | ASN135 |
| B | SER137 |
| B | GLN142 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD B 4005 |
| Chain | Residue |
| A | ARG222 |
| A | GLY313 |
| A | SER316 |
| B | THR87 |
| B | CYS88 |
| B | SER89 |
| B | GLN90 |
Functional Information from PROSITE/UniProt
| site_id | PS00014 |
| Number of Residues | 4 |
| Details | ER_TARGET Endoplasmic reticulum targeting sequence. HNEL |
| Chain | Residue | Details |
| A | HIS320-LEU323 | |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIsrqfv.CDsdrDCldg.SDEas...C |
| Chain | Residue | Details |
| B | CYS100-CYS122 | |
| B | CYS139-CYS163 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Domain: {"description":"LDL-receptor class A 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19520913","evidenceCode":"ECO:0000269"}]} |
