2FCW
Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the Receptor Associated Protein (RAP).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-2-macroglobulin receptor-associated protein | polymer | 109 | 12791.3 | 1 | UniProt (P30533) Pfam (PF06401) | Homo sapiens (human) | Alpha-2- MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP |
| 2 | B (B) | Low-density lipoprotein receptor | polymer | 80 | 8809.6 | 1 | UniProt (P01130) Pfam (PF00057) | Homo sapiens (human) | LDL receptor |
| 3 | C, D, E, J (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | F, G, K, L, M (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 5 | H, I (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A: 215 - 323 (UniProt: P30533)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | Glu 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21600.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 763.0 | |
| All* | Total formula weight | 22363.9 |
