2EZ7

Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: engineering proton transfer processes within the active site of an enzyme

Summary for 2EZ7

Entry DOI	10.2210/pdb2ez7/pdb
Descriptor	Carbonic anhydrase 2, MERCURY (II) ION, ZINC ION, ... (5 entities in total)
Functional Keywords	carbonic anhydrase ii, activators, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	29711.22
Authors	Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T. (deposition date: 2005-11-10, release date: 2006-07-18, Last modification date: 2024-02-14)
Primary citation	Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T. Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with L- and D-Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton-Transfer Processes within the Active Site of an Enzyme. Chemistry, 12:7057-7066, 2006 Cited by PubMed: 16807956 DOI: 10.1002/chem.200600159 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation