2DYH
Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2 transcription factor
Summary for 2DYH
Entry DOI | 10.2210/pdb2dyh/pdb |
Related | 1X2J 1X2R |
Descriptor | Kelch-like ECH-associated protein 1, Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2, SULFATE ION, ... (4 entities in total) |
Functional Keywords | bet-propeller, kelch motif, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transcription |
Biological source | Mus musculus (mouse) More |
Cellular location | Cytoplasm: Q9Z2X8 Cytoplasm, cytosol: Q60795 |
Total number of polymer chains | 2 |
Total formula weight | 37479.77 |
Authors | Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-09-14, release date: 2007-09-04, Last modification date: 2023-10-25) |
Primary citation | Tong, K.I.,Padmanabhan, B.,Kobayashi, A.,Shang, C.,Hirotsu, Y.,Yokoyama, S.,Yamamoto, M. Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response Mol.Cell.Biol., 27:7511-7521, 2007 Cited by PubMed: 17785452DOI: 10.1128/MCB.00753-07 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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