2DYH
Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2 transcription factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Kelch-like ECH-associated protein 1 | polymer | 318 | 35006.3 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) In PDB | Mus musculus (mouse) | Keap1, Cytosolic inhibitor of Nrf2 |
| 2 | B | Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2 | polymer | 15 | 1801.1 | 1 | UniProt (Q60795) In PDB | NF-E2-related factor 2, NFE2-related factor 2, Nuclear factor, erythroid derived 2, like 2 | |
| 3 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A: 309 - 624 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Met 308 | - | initiating methionine |
| Tyr 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36807.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 672.4 | |
| All* | Total formula weight | 37479.8 |
