2BQV
HIV-1 protease in complex with inhibitor AHA455
Summary for 2BQV
Entry DOI | 10.2210/pdb2bqv/pdb |
Related | 1HVC 2BB9 |
Descriptor | HIV-1 PROTEASE, 6-AMINO HEXANOIC ACID (3 entities in total) |
Functional Keywords | hydrolase/inhibitor, hydrolase-inhibitor complex, hiv-1 protease, inhibitor, drug design, hydrolase complex |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 |
Total number of polymer chains | 2 |
Total formula weight | 22196.21 |
Authors | Unge, T.,Ekegren, J.K.,Schenk, H.V.,Zreik Safa, M.,Wallberg, H.,Samuelsson, B.,Hallberg, A. (deposition date: 2005-04-28, release date: 2005-12-14, Last modification date: 2023-12-13) |
Primary citation | Ekegren, J.K.,Unge, T.,Safa, M.Z.,Wallberg, H.,Samuelsson, B.,Hallberg, A. A New Class of HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold. J.Med.Chem., 48:8098-, 2005 Cited by PubMed: 16335934DOI: 10.1021/JM050790T PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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