2BB9
Structure of HIV1 protease and AKC4p_133a complex.
Summary for 2BB9
Entry DOI | 10.2210/pdb2bb9/pdb |
Descriptor | Protease, 2-ETHOXYETHYL (1S,2S)-3-{(2S)-4-[(3AS,8S,8AR)-2-OXO-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2-D][1,3]OXAZOL-8-YL]-2-BENZYL-3-OXO-2,3-DIHYDRO-1H-PYRROL-2-YL}-1-BENZYL-2-HYDROXYPROPYLCARBAMATE (3 entities in total) |
Functional Keywords | protease, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22233.22 |
Authors | Smith III, A.B.,Charnley, A.K.,Kuo, L.C.,Munshi, S. (deposition date: 2005-10-17, release date: 2005-11-15, Last modification date: 2023-08-23) |
Primary citation | Smith III, A.B.,Charnley, A.K.,Harada, H.,Beiger, J.J.,Cantin, L.D.,Kenesky, C.S.,Hirschmann, R.,Munshi, S.,Olsen, D.B.,Stahlhut, M.W.,Schleif, W.A.,Kuo, L.C. Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains Bioorg.Med.Chem.Lett., 16:859-863, 2006 Cited by PubMed: 16298527DOI: 10.1016/j.bmcl.2005.11.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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