2BNU

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

Summary for 2BNU

• Entry DOI: 10.2210/pdb2bnu/pdb
• Descriptor: T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION (3 entities in total)
• Functional Keywords: superagonist peptide t-cell vaccines, receptor, t-cell, transmembrane, immunoglobulin domain, immune system/receptor, immune system-receptor complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Membrane ; Single-pass membrane protein : P01848 P01848
• Total number of polymer chains: 2
• Total formula weight: 49219.58

Authors

Chen, J.-L.,Stewart-Jones, G.,Bossi, G.,Lissin, N.M.,Wooldridge, L.,Choi, E.M.L.,Held, G.,Dunbar, P.R.,Esnouf, R.M.,Sami, M.,Boultier, J.M.,Rizkallah, P.J.,Renner, C.,Sewell, A.,Van Der Merwe, P.A.,Jackobsen, B.K.,Griffiths, G.,Jones, E.Y.,Cerundolo, V. (deposition date: 2005-04-04, release date: 2005-05-24, Last modification date: 2023-12-13)

• Primary citation: Chen, J.-L.,Stewart-Jones, G.,Bossi, G.,Lissin, N.M.,Wooldridge, L.,Choi, E.M.L.,Held, G.,Dunbar, P.R.,Esnouf, R.M.,Sami, M.,Boulter, J.M.,Rizkallah, P.,Renner, C.,Sewell, A.,Van Der Merwe, P.A.,Jakobsen, B.K.,Griffiths, G.,Jones, E.Y.,Cerundolo, V.; Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines.; J.Exp.Med., 201:1243-, 2005; PubMed: 15837811; DOI: 10.1084/JEM.20042323

Experimental method

X-RAY DIFFRACTION (1.4 Å)