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2BCS

DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp

Summary for 2BCS
Entry DOI10.2210/pdb2bcs/pdb
Related2BCQ 2BCR 2BCU 2BCV
Descriptor5'-D(*GP*CP*CP*G)-3', 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*CP*TP*AP*CP*TP*G)-3', ... (8 entities in total)
Functional Keywordsmisalignment, extrahelical, mutagenesis, mutation, deletion, streisinger, slippage, transferase, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9UGP5
Total number of polymer chains4
Total formula weight44681.62
Authors
Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2005-10-19, release date: 2006-03-07, Last modification date: 2023-08-23)
Primary citationGarcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Pedersen, L.C.,Kunkel, T.A.
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Cell(Cambridge,Mass.), 124:331-342, 2006
Cited by
PubMed: 16439207
DOI: 10.1016/j.cell.2005.10.039
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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