2AD5
Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution.
Summary for 2AD5
Entry DOI | 10.2210/pdb2ad5/pdb |
Related | 1S1M 1VCM |
Descriptor | CTP synthase, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | rossmann fold, p-loop atpase, interfacial active site, ligase |
Biological source | Escherichia coli K12 |
Total number of polymer chains | 2 |
Total formula weight | 122763.28 |
Authors | Endrizzi, J.A.,Kim, H.,Anderson, P.M.,Baldwin, E.P. (deposition date: 2005-07-19, release date: 2005-11-01, Last modification date: 2023-08-23) |
Primary citation | Endrizzi, J.A.,Kim, H.,Anderson, P.M.,Baldwin, E.P. Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,). Biochemistry, 44:13491-13499, 2005 Cited by PubMed: 16216072DOI: 10.1021/bi051282o PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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