2AD5
Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CTP synthase | polymer | 545 | 60447.0 | 2 | UniProt (P0A7E5) Pfam (PF06418) Pfam (PF00117) Pfam (PF07722) | Escherichia coli K12 | UTP--ammonia ligase, CTP synthetase |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, G (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | E, H (A, B) | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 2 | Chemie (CTP) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120894.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1869.3 | |
| All* | Total formula weight | 122763.3 |
