28OQ

Protein Kinaze domain PAK1 complexed with NVS inhibitor

This is a non-PDB format compatible entry.

Summary for 28OQ

• Entry DOI: 10.2210/pdb28oq/pdb
• Descriptor: Serine/threonine-protein kinase PAK 1, CHLORIDE ION, (3~{S})-3-[(~{Z})-[11-[2,2-bis(fluoranyl)ethyl]-8-chloranyl-3-fluoranyl-5~{H}-benzo[b][1,4]benzodiazepin-6-ylidene]amino]-~{N}-propan-2-yl-pyrrolidine-1-carboxamide, ... (5 entities in total)
• Functional Keywords: protein kinaze, complex wwth inhibitor, pak1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 67349.36

Authors

Nowak, E.,Nowotny, M. (deposition date: 2026-02-11, release date: 2026-04-01)

• Primary citation: Yu, H.; Rational Discovery of Therapeutic PAK1 Allosteric Activators; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.28 Å)