28MS
X-ray structure of the adduct between human serum transferrin with Fe3+ bound at the C-lobe and dirhodium tetraacetate
This is a non-PDB format compatible entry.
Summary for 28MS
| Entry DOI | 10.2210/pdb28ms/pdb |
| Descriptor | Serotransferrin, FE (III) ION, MALONATE ION, ... (8 entities in total) |
| Functional Keywords | human transferrin, diruthenium, iron, drug delivery, protein-metal interaction, metal transport |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 80207.85 |
| Authors | Ferraro, G.,Merlino, A. (deposition date: 2026-02-08, release date: 2026-03-11, Last modification date: 2026-03-18) |
| Primary citation | Banneville, A.S.,Ferraro, G.,D'Elia, R.,Cornaciu-Hoffmann, I.,Pica, A.,Merlino, A. Ru and Rh binding sites in the structure of human serum transferrin with Fe 3+ bound at the C-lobe. Dalton Trans, 55:4051-4056, 2026 Cited by PubMed Abstract: Ru and Rh binding sites in the structure of human serum transferrin with Fe bound at the C-lobe were identified by X-ray crystallography. Several His side chains and one Met are involved in the recognition of the metal ions by the protein. PubMed: 41738634DOI: 10.1039/d6dt00205f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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