28KE

Cryo-EM structure of the human holo-TFIIH-XPC-XPA complex bound to bulky lesion-mimic DNA

Summary for 28KE

• Entry DOI: 10.2210/pdb28ke/pdb
• Related: 28JM 28JS 28JV
• EMDB information: 56544 56551 56566 56573
• Descriptor: General transcription and DNA repair factor IIH helicase subunit XPB, DNA repair protein complementing XP-A cells, DNA lesion strand, ... (14 entities in total)
• Functional Keywords: nucleotide excision repair, dna repair, helicase, transcription factor, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 595869.50

Authors

de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J. (deposition date: 2026-02-04, release date: 2026-05-06)

• Primary citation: de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J.; Visualisation of stepwise de-repression of TFIIH in global-genome nucleotide excision repair; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.6 Å)