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27XK

A cryo-EM structure of GLP1-Y11-GLP1R-Gs complex

Summary for 27XK
Entry DOI10.2210/pdb27xk/pdb
EMDB information81535
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Glucagon-like peptide 1(7-36), ... (6 entities in total)
Functional Keywordsgpcr, glp1, membrane protein
Biological sourceBos taurus
More
Total number of polymer chains6
Total formula weight159534.14
Authors
Zhao, L.,Yuan, Q. (deposition date: 2026-06-16, release date: 2026-07-01)
Primary citationZhao, L.,Yuan, Q.
N-terminally modified GLP1R agonists drive G protein bias via extracellular loop 3 displacement
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.64 Å)
Structure validation
No wwPDB Validation report is currently available for this entry.

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PDB entries from 2026-07-01

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