26JZ

Cryo-EM structure of Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with 5'/3' vRNA dual-promotor

Summary for 26JZ

• Entry DOI: 10.2210/pdb26jz/pdb
• Related: 22TE 22TR
• EMDB information: 80706
• Descriptor: RNA-directed RNA polymerase L, 5' vRNA promoter, 3' vRNA promoter, ... (6 entities in total)
• Functional Keywords: polymerase, rna binding protein/rna, rna binding protein-rna complex
• Biological source: Orthonairovirus haemorrhagiae; More
• Total number of polymer chains: 3
• Total formula weight: 464953.57

Authors

Ma, J.,Yang, K.,Wu, H.,Liu, X.,Liang, Z. (deposition date: 2026-05-04, release date: 2026-08-19)

• Primary citation: Yang, K.,Wu, H.,Liu, X.,Ma, J.; Cryo-EM structures of CCHFV polymerase reveal a stepwise initiation stabilization pathway and a dual-site inhibition mechanism; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.65 Å)