26FF

Crystal structure of the second bromodomain (BD2) of human Bromodomain-containing protein 4 (BRD4) complexed with 2-(benzylamino)pyrimidin-4(3H)-one

This is a non-PDB format compatible entry.

Summary for 26FF

• Entry DOI: 10.2210/pdb26ff/pdb
• Descriptor: Bromodomain-containing protein 4, 2-[(phenylmethyl)amino]-1~{H}-pyrimidin-6-one (3 entities in total)
• Functional Keywords: brd4-bd2, inhibitor, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 30523.11

Authors

Prasad, T.K.,Sriram Prakash, B.,Neelagandan, K. (deposition date: 2026-04-29, release date: 2026-09-30)

• Primary citation: Baskaran, S.P.,Subramani, Y.V.,Bairy, S.G.,Prasad, T.K.,Kumar, V.,Sridhar, A.,Padmanabhan, B.,Kamariah, N.; Fragment-Based; Acs Omega, 11:56159-56169, 2026; DOI: 10.1021/acsomega.6c06516

Experimental method

X-RAY DIFFRACTION (2.4 Å)