26FF
Crystal structure of the second bromodomain (BD2) of human Bromodomain-containing protein 4 (BRD4) complexed with 2-(benzylamino)pyrimidin-4(3H)-one
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 4 | polymer | 130 | 15060.3 | 2 | UniProt (O60885) | Homo sapiens (human) | Protein HUNK1 |
| 2 | C, D (A, B) | 2-[(phenylmethyl)amino]-1~{H}-pyrimidin-6-one | non-polymer | 201.2 | 2 | Chemie (A1MGQ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B: 333 - 460 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 331 | - | expression tag |
| Met 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30120.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 402.4 | |
| All* | Total formula weight | 30523.1 |
