25VX

Crystal Structure of MYST histone acetyltransferase KAT6A in complex with inhibitor Compound 9

This is a non-PDB format compatible entry.

Summary for 25VX

• Entry DOI: 10.2210/pdb25vx/pdb
• Related: 22TG
• Descriptor: Histone acetyltransferase KAT8, 2,6-dimethoxy-~{N}-(5-phenyl-3,4-dihydro-2~{H}-pyrano[2,3-e][1,2]benzoxazol-9-yl)benzenesulfonamide (3 entities in total)
• Functional Keywords: kat6a, inhibitor, small molecule, drug discovery, acetyltransferase, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 32412.34

Authors

NarasimhaRao, K.,Vijayshankar, N.,SumalathaRani, T.,Kalishankar, B.,Chandregowda, V.,Chandrasekar, A.,Susanta, S.,Raymond, A.N.,David, C.M. (deposition date: 2026-04-20, release date: 2026-05-06)

• Primary citation: NarasimhaRao, K.,Vijayshankar, N.,SumalathaRani, T.,Kalishankar, B.,Chandregowda, V.,Chandrasekar, A.,Susanta, S.,Raymond, A.N.,David, C.M.; Crystal Structure of MYST histone acetyltransferase KAT6A in complex with Compound 9; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.29 Å)