25CH

Structure of hTRPC3 T561A mutant in the partially open state with C4 symmetry

This is a non-PDB format compatible entry.

Summary for 25CH

• Entry DOI: 10.2210/pdb25ch/pdb
• EMDB information: 80011
• Descriptor: Short transient receptor potential channel 3, CALCIUM ION, ZINC ION, ... (4 entities in total)
• Functional Keywords: trpc3, open state, 4f peptide, metal transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 401513.80

Authors

Chen, L.,Zang, J. (deposition date: 2026-03-29, release date: 2026-11-11)

• Primary citation: Zang, J.,Tan, Y.,Chen, Y.,Guo, W.,Zhao, X.,Peng, H.,Chen, L.; Structural mechanism of TRPC3 channel activation by the moonwalker mutation.; Cell Discov, 12:-, 2026; PubMed: 42957638; DOI: 10.1038/s41421-026-00936-y

Experimental method

ELECTRON MICROSCOPY (2.93 Å)