25CH

Structure of hTRPC3 T561A mutant in the partially open state with C4 symmetry

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Short transient receptor potential channel 3	polymer	866	99571.8	4	UniProt (Q13507)	Homo sapiens (human)	TrpC3,Transient receptor protein 3,TRP-3,hTrp-3,hTrp3
2	E, F, G, J, K... (A, B, C, D)	CALCIUM ION	non-polymer		40.1	12	Chemie (CA) PubChem (271)
3	H, M, R, W (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN) PubChem (32051)
4	I, N, S, X (A, B, C, D)	[(2~{S})-2-[(~{E})-octadec-9-enoyl]oxy-3-oxidanyl-propyl] octadec-9-enoate	non-polymer		621.0	4	Chemie (A1L5I)

Sequence modifications

A, B, C, D: 1 - 836 (UniProt: Q13507)

PDB	External Database	Details
Trp -29	-	expression tag
Ser -28	-	expression tag
His -27	-	expression tag
Pro -26	-	expression tag
Gln -25	-	expression tag
Phe -24	-	expression tag
Glu -23	-	expression tag
Lys -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Gly -19	-	expression tag
Asp -18	-	expression tag
Tyr -17	-	expression tag
Lys -16	-	expression tag
Asp -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Lys -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Trp -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
Pro -4	-	expression tag
Gln -3	-	expression tag
Phe -2	-	expression tag
Glu -1	-	expression tag
Lys 0	-	expression tag
Ala 561	Thr 646	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	398287.3
Non-Polymers*	Number of molecules	20
	Total formula weight	3226.5
All*	Total formula weight	401513.8

*Water molecules are not included.