24RC

Cryo-EM structure of human sodium pump W931R mutant in K+-occluded E2-Pi state

Summary for 24RC

• Entry DOI: 10.2210/pdb24rc/pdb
• EMDB information: 69776
• Descriptor: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-3, TETRAFLUOROALUMINATE ION, ... (8 entities in total)
• Functional Keywords: p-type atpase, sodium pump, mutant, micelle, hypomagnesimia, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 145020.07

Authors

Fujimura, R.,Gopalasingam, C.C.,Abe, K. (deposition date: 2026-03-17, release date: 2026-05-27)

• Primary citation: Artigas, P.,Abe, K.; On the mechanism of hypomagnesimia with treatment-resistant seizures cansed by variants of the Na+,K+-ATPase alpha1 subunit (ATP1A1); To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.61 Å)