24OS

Crystal Structure of BRD3 BD1 domain in complex with small molecule inhibitor IBET-762

Summary for 24OS

• Entry DOI: 10.2210/pdb24os/pdb
• Related: 9x7c
• Descriptor: Bromodomain-containing protein 3, 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide (3 entities in total)
• Functional Keywords: brd3, cancer ligand bound, inhibitor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 29763.25

Authors

Jwala, N.,Chandrasekhar, A.,NarasimhaRao, K. (deposition date: 2026-03-13, release date: 2026-03-25)

• Primary citation: Jwala, N.,Chandrasekhar, A.,NarasimhaRao, K.; Crystal Structure of BRD3 BD1 domain in complex with small molecule inhibitor IBET-762; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)