24OS
Crystal Structure of BRD3 BD1 domain in complex with small molecule inhibitor IBET-762
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 3 | polymer | 122 | 14457.7 | 2 | UniProt (Q15059) | Homo sapiens (human) | RING3-like protein |
| 2 | C, D (A, B) | 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide | non-polymer | 423.9 | 2 | Chemie (EAM) PubChem (46943432) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 143 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | - | expression tag |
| Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28915.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 847.8 | |
| All* | Total formula weight | 29763.2 |
