24FX

Crystal Structure of FtmOx1 L222F complexes with alkylamine derivative

This is a non-PDB format compatible entry.

Summary for 24FX

• Entry DOI: 10.2210/pdb24fx/pdb
• Descriptor: Verruculogen synthase, ~{N}-[(4-hydroxyphenyl)methyl]-~{N}-[2-(4-methoxyphenyl)ethyl]morpholine-4-carboxamide, 2-OXOGLUTARIC ACID, ... (6 entities in total)
• Functional Keywords: c-h oxidation, hydroxylation, non-heme iron enzyme, oxidoreductase
• Biological source: Aspergillus fumigatus
• Total number of polymer chains: 2
• Total formula weight: 65538.69

Authors

Liang, H.R. (deposition date: 2026-03-03, release date: 2026-10-21)

• Primary citation: Zhang, J.,Liang, H.,Shang, A.,Wu, C.,Yu, J.,Zhang, G.,Chen, Y.,Wang, M.W.,Tang, G.L.,Sun, A.,Zhou, S.,Liu, H.; FtmOx1-catalyzed diverse C(sp3)-H oxyfunctionalization enables versatile late-stage diversification of phenethylamines and tetrahydroisoquinolines; Nat Commun, 2026; DOI: 10.1038/s41467-026-78405-z

Experimental method

X-RAY DIFFRACTION (1.65 Å)