24FX
Crystal Structure of FtmOx1 L222F complexes with alkylamine derivative
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Verruculogen synthase | polymer | 285 | 32132.8 | 2 | UniProt (B9WZX5) | Aspergillus fumigatus | Fumitremorgin biosynthesis protein F |
| 2 | C, F (A, B) | ~{N}-[(4-hydroxyphenyl)methyl]-~{N}-[2-(4-methoxyphenyl)ethyl]morpholine-4-carboxamide | non-polymer | 370.4 | 2 | Chemie (A1EKG) | |||
| 3 | D, G (A, B) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 2 | Chemie (AKG) PubChem (51) | |||
| 4 | E, I (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) PubChem (104729) | |||
| 5 | H (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 290 (UniProt: B9WZX5)
| PDB | External Database | Details |
|---|---|---|
| Val 89 | Ile 89 | conflict |
| Val 148 | Ile 148 | conflict |
| Phe 222 | Leu 222 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64265.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1273.1 | |
| All* | Total formula weight | 65538.7 |
