22WP

local reifnement of 5HT2AR-miniGq heterotrimer in complex with a psychedelic psilocin

Summary for 22WP

• Entry DOI: 10.2210/pdb22wp/pdb
• EMDB information: 68735
• Descriptor: 5-hydroxytryptamine receptor 2A, 3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-ol (2 entities in total)
• Functional Keywords: gpcr, serotonin receptor, membrane protein, 5ht2ar
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37711.54

Authors

Tang, L.,Ji, X.,Cheng, J.,Wang, S. (deposition date: 2026-01-26, release date: 2026-09-16)

• Primary citation: Tang, L.,Ji, X.,Wang, Y.,Cao, D.,Li, H.,He, L.,Cheng, J.,Wang, S.; Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.33 Å)