22WP
local reifnement of 5HT2AR-miniGq heterotrimer in complex with a psychedelic psilocin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5-hydroxytryptamine receptor 2A | polymer | 336 | 37507.3 | 1 | UniProt (P28223) Pfam (PF00001) | Homo sapiens (human) | 5-HT-2,5-HT-2A,Serotonin receptor 2A |
| 2 | B (A) | 3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-ol | non-polymer | 204.3 | 1 | Chemie (91Q) |
Sequence modifications
A: 66 - 394 (UniProt: P28223)
| PDB | External Database | Details |
|---|---|---|
| Gly 59 | - | expression tag |
| Pro 60 | - | expression tag |
| Gly 61 | - | expression tag |
| Ser 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Ser 64 | - | expression tag |
| Gly 65 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37507.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 204.3 | |
| All* | Total formula weight | 37711.5 |
