22JX

Cryo-EM structure of the mGlu5-beta-arrestin 1 complex

Summary for 22JX

• Entry DOI: 10.2210/pdb22jx/pdb
• EMDB information: 68388
• Descriptor: Metabotropic glutamate receptor 5, beta-arrestin 1, scFv30, ... (5 entities in total)
• Functional Keywords: gpcr, metabotropic glutamate receptor, beta-arrestin, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 458939.12

Authors

Lin, S.,Zhang, C.,Wei, J.,Chen, K.,Feng, Y.,Wang, Z.,Chu, X.,Yi, C.,Ma, L.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2026-01-14, release date: 2026-09-09)

• Primary citation: Lin, S.,Zhang, C.,Wei, J.,Yu, J.,Li, S.,Xu, J.,Su, J.,Chen, K.,Feng, Y.,Wang, Z.,Chu, X.,Yi, C.,Ma, L.,Han, S.,Zhang, H.,Shui, W.,Zhao, Q.,Wu, B.; Subtype-dependent arrestin engagement of the metabotropic glutamate receptors; To be published,

Experimental method

ELECTRON MICROSCOPY (3.7 Å)