22ES

Gi bound kappa-opioid receptor in complex with difelikefalin

This is a non-PDB format compatible entry.

Summary for 22ES

• Entry DOI: 10.2210/pdb22es/pdb
• EMDB information: 68217
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Kappa-type opioid receptor, ... (7 entities in total)
• Functional Keywords: gpcr, opioid receptor, signaling protein/immune system, signaling protein-immune system complex
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 162653.67

Authors

Zhang, H.,Wang, R.,Shi, P.,He, X.,Zhu, Q.,Xu, Y.,Yuan, Q.,Hu, W.,Wu, K.,Zheng, Y.,Zhou, L.,Liang, J.,Lv, P.,Xu, Z.,Zhuang, Y.,Xu, H.,Wang, Y.,Tian, C. (deposition date: 2026-01-08, release date: 2026-05-06)

• Primary citation: Zhang, H.,Wang, R.,Shi, P.,He, X.,Zhu, Q.,Xu, Y.,Yuan, Q.,Hu, W.,Wu, K.,Zheng, Y.,Zhou, L.,Liang, J.,Lv, P.,Xu, Z.,Zhuang, Y.,Xu, H.,Wang, Y.,Tian, C.; Gi bound kappa-opioid receptor in complex with difelikefalin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.43 Å)