22EM

Gi bound kappa-opioid receptor in complex with beta01

Summary for 22EM

Entry DOI	10.2210/pdb22em/pdb
EMDB information	68208
Descriptor	Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
Functional Keywords	gpcr, opioid receptor, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	159378.25
Authors	Zhang, H.,Wang, R.,Shi, P.,He, X.,Zhu, Q.,Xu, Y.,Yuan, Q.,Hu, W.,Wu, K.,Zheng, Y.,Zhou, L.,Liang, J.,Lv, P.,Xu, Z.,Zhuang, Y.,Xu, H.,Wang, Y.,Tian, C. (deposition date: 2026-01-08, release date: 2026-05-06)
Primary citation	Zhang, H.,Wang, R.,Shi, P.,He, X.,Zhu, Q.,Xu, Y.,Yuan, Q.,Hu, W.,Wu, K.,Zheng, Y.,Zhou, L.,Liang, J.,Lv, P.,Xu, Z.,Zhuang, Y.,Xu, H.,Wang, Y.,Tian, C. Gi bound kappa-opioid receptor in complex with beta01 To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.86 Å)

Structure validation