21ZX

Crystal structure of Gephyrin E domain with PX-RICS peptide

Summary for 21ZX

• Entry DOI: 10.2210/pdb21zx/pdb
• Descriptor: Isoform 5 of Gephyrin, Rho GTPase-activating protein 32, GLYCEROL, ... (5 entities in total)
• Functional Keywords: px-rics, arhgap32, gephyrin, complex, protein binding
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 196368.26

Authors

Bai, G.,Zhang, M.,Yang, W. (deposition date: 2026-01-05, release date: 2026-07-15)

• Primary citation: Bai, G.,Zhang, M.,Yang, W.; The ARHGAP32 isoform PX-RICS is specifically targeted to inhibitory synapses by binding to gephyrin; Proc.Natl.Acad.Sci.USA, 2026; DOI: 10.1073/pnas.2601488123

Experimental method

X-RAY DIFFRACTION (2.2 Å)