21TL

Enterovirus 71 Polymerase Elongation Complex with a remdesivir nucleotide at product strand positions +1 (C1S5 form)

Summary for 21TL

• Entry DOI: 10.2210/pdb21tl/pdb
• Descriptor: Enterovirus 71 polymerase, RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*CP*UP*CP*U*(F86))-3'), RNA (33-MER), ... (7 entities in total)
• Functional Keywords: enterovirus, rna-dependent rna polymerase, elongation complex, remdesivir nucleotide, transferase
• Biological source: Enterovirus A71; More
• Total number of polymer chains: 3
• Total formula weight: 69617.89

Authors

Wang, M.,Li, R.,Gong, P. (deposition date: 2025-12-23, release date: 2026-10-07)

• Primary citation: Li, R.,Shao, Q.,Wang, M.,Feng, C.,Xu, Q.,Wang, Q.,Shang, L.; Highly effective viral RdRP translocation hindrance by the remdesivir nucleotide; Nucleic Acids Res., 2026; DOI: 10.1093/nar/gkag957

Experimental method

X-RAY DIFFRACTION (2.7 Å)