21FS

Cryo-EM structure of human organic solute transporter OSTalpha/beta

Summary for 21FS

• Entry DOI: 10.2210/pdb21fs/pdb
• EMDB information: 67632
• Descriptor: Organic solute transporter subunit alpha, Organic solute transporter subunit beta, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: membrane protein, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 115613.57

Authors

Xu, K.,Hou, W.T. (deposition date: 2025-12-11, release date: 2026-11-11)

• Primary citation: Xu, K.,Li, B.R.,Huang, G.Y..,Wang, F.F.,Wang, J.,Wang, B.,Chu, C.Y.,Chen, G.T.,Zhou, C.Z.,Chen, Y.,Hou, W.T.; Structural basis of bile acid lateral diffusion facilitated by the OST alpha / beta transporter; Nat Commun, 2026; DOI: 10.1038/s41467-026-78517-6

Experimental method

ELECTRON MICROSCOPY (2.68 Å)